Renal Disorders Case Lab

Afferent arteriole Filtrate Urine Hyperfiltering nephron Lost nephron

Nephron and GFR simulator

Move the sliders and watch the pressure inside the glomerulus, the GFR, and the blood tests change. Numbers are a simple teaching model of an adult.

Mean arterial pressure (MAP) 93 mmHg

40100160

Afferent arteriole (in) normal

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Efferent arteriole (out) normal

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Working nephrons 100%

5%50%100%

Kidney readouts
Measure	Value

Scenarios

Challenges

Red blood cells Albumin Immune complexes Podocyte foot processes Basement membrane

Filter damage simulator

Damage the glomerular filter in two different ways. Inflammation tears it (nephritic). Podocyte injury makes it leaky to protein (nephrotic). Watch what ends up in the urine and what happens to the patient.

Inflammation (immune complexes) 0%

Podocyte damage 0%

Filter readouts
Measure	Value

Renal and Urinary Disorders Case Lab

Cards to sort